Sugar acids and derivatives
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 1ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies
Medchemexpress LLC UDP-glucuronic acid (trisodium) | 63700-19-6 | 1 ML
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates found across various biological kingdoms. These glycoconjugates include mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. This product has also been shown to promote the migration of liver cancer cells (Huh7, SK-Hep1, and SNU449) through the induction of the EMT process.
- Critical precursor for essential glycoconjugates
- Supports the formation of mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids
- Induces cell migration in liver cancer cell lines
- Decreases E-cadherin levels and increases vimentin levels in liver cancer cells
- Purity of 99.87%
- Appearance as a white to off-white solid
- For research use only
Medchemexpress LLC Azido-PEG4-beta-D-glucose | 1609083-15-9 | 99.9% | C14H27N3O9 | 10MG
Azido-PEG4-beta-D-glucose is an azide-terminated PEG4 linker bearing a beta-D-glucose moiety, used as a click chemistry reagent and PROTAC linker. It enables efficient conjugation to alkyne-bearing molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and to strained alkynes via strain-promoted alkyne-azide cycloaddition (SPAAC). The material is supplied at high purity for chemical biology and synthesis applications.
- Azide-terminated PEG4 linker for efficient bioconjugation.
- Beta-D-glucose unit enhances solubility and potential targeting.
- Compatible with CuAAC and SPAAC click reactions.
- High purity suitable for synthesis and analytical workflows.
- Stable under sealed storage at -20°C; follow solvent storage guidelines.
Medchemexpress LLC 4-methylumbelliferyl α-L-iduronide | 66966-09-4 | MFCD00135894 | 99.0% | 352.29 g/mol | C16H16O9 | 1 MG
4-Methylumbelliferyl α-L-iduronide is a fluorogenic biochemical reagent used as a substrate to measure α-L-iduronidase activity. Enzymatic cleavage releases 4-methylumbelliferone, producing a fluorescent signal for sensitive fluorometric assays in lysosomal enzyme studies and biochemical assay development.
- Fluorogenic substrate for α-L-iduronidase assays.
- Enables sensitive fluorometric detection via 4-methylumbelliferone release.
- Suitable for enzyme kinetics and biochemical assay development.
- Available in small research quantities (μg-mg scale).
- Store protected from light at -20°C; in solvent, -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Hederacoside D | 760961-03-3 | 99.5% | 1075.24 | 25 MG
Hederacoside D is one of the bioactive saponins from Hedera helix, playing pivotal roles in the overall biological activity. It is intended for research use only.
- Appearence: Solid
- Color: White to off-white
- Structure classification: Terpenoids, Triterpenes
- Initial source: Plants, Araliaceae, Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd.
- Solubility: In DMSO: 100 mg/mL (93.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
- Pharmacokinetic behavior successfully applied in rats after oral and intravenous administration.
TARGETMOL CHEMICALS INC Terrestrosin D 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of actions for the observed antitumor and antiangiogenic activities of terrestrosin D. Purity 99.54%
Chem-Impex International, Inc. 4-Methylumbelliferyl-b-D-glucuronide hydrate | 6160-80-1 | MFCD09039280 | 5G
4-Methylumbelliferyl-b-D-glucuronide hydrate, 6160-80-1, MFCD09039280, 5G
Chem-Impex International, Inc. 4-Methylumbelliferyl-b-D-glucuronide hydrate | 6160-80-1 | MFCD09039280 | 1G
4-Methylumbelliferyl-b-D-glucuronide hydrate, 6160-80-1, MFCD09039280, 1G
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Medchemexpress LLC Beta-Acetoxyisovalerylshikonin | 69091-17-4 | 25 MG
Beta-Acetoxyisovalerylshikonin is a naphthoquinone derivative isolated from Arnebia euchroma.
- High purity: 99.57%
- Molecular weight: 430.45
- Molecular formula: C23H26O8
- Appearance: Brown to black solid
- Used in simultaneous densitometric determination of related compounds
- Applied in isolation and purification processes using preparative HPLC
Medchemexpress LLC Heparin calcium (MW 3600-5000) | 37270-89-6 | 3600-5000 Da | 100 MG
Heparin calcium (MW 3600-5000) is the calcium salt form of heparin, a polydisperse sulfated glycosaminoglycan anticoagulant supplied as a solid for research use. It acts by binding antithrombin III, accelerating inactivation of thrombin and other activated clotting factors to prevent fibrin formation. Supplied in low-molecular-weight fractions with an average molecular weight range of 3600-5000 Da.
- Anticoagulant action via antithrombin III binding.
- Low molecular weight range: 3600-5000 Da.
- Calcium salt supplied as a solid form.
- Intended for research use only, not for clinical use.
- Common pack size: 100 mg.
Medchemexpress LLC Lafadofensine (D-(-)-Mandelic acid) | 99.9% | C32H32F2N2O6 | 25 MG
Lafadofensine (D-(-)-Mandelic acid) is a monoamines reuptake inhibitor that demonstrates sufficient effects after short-term administration. This product is for research use only.
- Purity of 99.95% (LCMS)
- Molecular weight: 578.60
- Chemical formula: C32H32F2N2O6
- Appearance: White to off-white solid
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC JBI-589 | 2308504-22-3 | 99.8% | 481.56 g·mol⁻¹ | C29H28FN5O | 10 MG
JBI-589 is a non-covalent, isoform-selective inhibitor of peptidylarginine deiminase 4 (PAD4) with oral bioavailability, developed for preclinical cancer and immunology research. It reduces CXCR2 expression, blocks neutrophil chemotaxis, and has shown activity in reducing primary tumor growth and metastasis in experimental studies.
- Selective PAD4 inhibition with demonstrated activity in cellular assays.
- Orally bioavailable small molecule suitable for in vivo studies.
- High chemical purity for research use.
- Soluble in DMSO at high concentrations (requires sonication).
- Stable when stored under recommended powder and solvent conditions.
Medchemexpress LLC Heparin calcium | 37270-89-6 | MFCD00131296 | ≥98.0% | 3600-5000 | Not specified (heterogeneous polysaccharide; no single chemical formula) | 25 MG
Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin anticoagulant supplied for research use. It binds antithrombin III to inactivate thrombin and other activated clotting factors, preventing fibrin formation. The material is provided as a white to off-white solid with good aqueous solubility and is intended for laboratory assays involving anticoagulation or coagulation pathway studies.
- Intended for research use only.
- Anticoagulant that binds antithrombin III to inhibit coagulation.
- Molecular weight range 3600-5000.
- Supplied as a white to off-white solid.
- Soluble in water (≈200 mg/mL with ultrasonication).
- Store sealed and dry at 4 °C; in solution, store at -20 °C to -80 °C per guidelines.
- Typical purity ≥98% (batch-specific certificate of analysis available).
- Available in small laboratory package sizes (example: 25 mg).
BIOHIPPO T-bet-TAR-Puro LV
T-bet-TAR-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures